MOLECULAR CHANGES TRACKING THROUGH MULTISCALE FLUORESCENCE MICROSCOPY DIFFERENTIATE MENINGIOMA GRADES AND NON-TUMORAL BRAIN TISSUES

Molecular changes tracking through multiscale fluorescence microscopy differentiate Meningioma grades and non-tumoral brain tissues

Abstract Meningioma is the most common primary intracranial extra-axial tumor.Total surgical removal is the standard therapeutic method to treat this type of brain tumors.However, the risk of recurrence depends on the tumor grade and the extent of the resection including the infiltrated dura mater and, if necessary, the infiltrated bone.Therefore,

read more

2070 High-intensity focused ultrasound (HIFU) can be used synergistically with tamoxifen to overcome resistance in preclinical and patient derived xenograft models

OBJECTIVES/SPECIFIC AIMS: The goal of this study is to evaluate a potential strategy to overcome tamoxifen (tam) resistance by using tam in combination with high-intensity focused ultrasound (HIFU).Tam is the most commonly used anti-cancer therapeutic agent in estrogen receptor positive (ER+) breast cancer (BC) which accounts for ~70% of BC cases.T

read more

Study on hydrogen stratification and erosion process in Chinese SMR containment under severe accident scenario

During postulated severe accident, large amount of hydrogen-vapor mixture will be released into the containment and inflammable gas mixture may form.Once the gas will be ignited, the generated pressure loads can jeopardize the integrity of Beauty the internal structures.As the local accumulation of high content hydrogen related much to the stratifi

read more